A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance of circulating autoantibodies to pancreatic islets. However, almost nothing is known about events leading to this islet autoimmunity. Previous epidemiological and genetic data have associated viral infections and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ferreira, Ricardo C., Guo, Hui, Coulson, Richard M.R., Smyth, Deborah J., Pekalski, Marcin L., Burren, Oliver S., Cutler, Antony J., Doecke, James D., Flint, Shaun, McKinney, Eoin F., Lyons, Paul A., Smith, Kenneth G.C., Achenbach, Peter, Beyerlein, Andreas, Dunger, David B., Clayton, David G., Wicker, Linda S., Todd, John A., Bonifacio, Ezio, Wallace, Chris, Ziegler, Anette-G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2014
Pynciau:
Genetics/Genomes/Proteomics/Metabolomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066333/
https://ncbi.nlm.nih.gov/pubmed/24561305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1777
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