A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance of circulating autoantibodies to pancreatic islets. However, almost nothing is known about events leading to this islet autoimmunity. Previous epidemiological and genetic data have associated viral infections and...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ferreira, Ricardo C., Guo, Hui, Coulson, Richard M.R., Smyth, Deborah J., Pekalski, Marcin L., Burren, Oliver S., Cutler, Antony J., Doecke, James D., Flint, Shaun, McKinney, Eoin F., Lyons, Paul A., Smith, Kenneth G.C., Achenbach, Peter, Beyerlein, Andreas, Dunger, David B., Clayton, David G., Wicker, Linda S., Todd, John A., Bonifacio, Ezio, Wallace, Chris, Ziegler, Anette-G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2014
Témata:
Genetics/Genomes/Proteomics/Metabolomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066333/
https://ncbi.nlm.nih.gov/pubmed/24561305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1777
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky