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Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells

AIM: To determine if proteasome inhibition induces apoptosis in human cholangiocarcinoma cells, and if so, to elucidate the cellular mechanisms. METHODS: Studies were performed in the human KMCH, KMBC, and Mz-ChA-1 cholangiocarcinoma, and normal rat cell lines. MG132, a peptide aldehyde, which inhib...

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書誌詳細
主要な著者: Ustundag, Yucel, Bronk, Steven F, Gores, Gregory J
フォーマット: Artigo
言語:Inglês
出版事項: Baishideng Publishing Group Co., Limited 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065919/
https://ncbi.nlm.nih.gov/pubmed/17352013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i6.851
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