Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.

Eitemau Tebyg

• Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase.
  gan: Yaron, A, et al.
  Cyhoeddwyd: (1997)
• In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B.
  gan: Alkalay, I, et al.
  Cyhoeddwyd: (1995)
• A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.
  gan: Traenckner, E B, et al.
  Cyhoeddwyd: (1994)
• Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression
  Cyhoeddwyd: (1996)
• Ubiquitination and Degradation of the Inhibitors of NF-κB
  gan: Kanarek, Naama, et al.
  Cyhoeddwyd: (2010)