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Synchronization of sinoatrial node pacemaker cell clocks and its autonomic modulation impart complexity to heart beating intervals Short title: Beating-rate variability of sinoatrial node cells

BACKGROUND: A reduction of complexity of heart-beat interval variability (BIV) that is associated with an increased morbidity and mortality in cardiovascular disease states is thought to derive from the balance of sympathetic and parasympathetic neural impulses to the heart. But rhythmic clock-like...

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Detalhes bibliográficos
Main Authors: Yaniv, Yael, Ahmet, Ismayil, Liu, Jie, Lyashkov, Alexey E., Guiriba, Toni-Rose, Okamoto, Yosuke, Ziman, Bruce D., Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065846/
https://ncbi.nlm.nih.gov/pubmed/24713624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2014.03.049
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