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Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life
Neonates often generate incomplete immunity against intracellular pathogens, although the mechanism of this defect is poorly understood. An important question is whether the impaired development of memory CD8+ T cells in neonates is due to an immature priming environment or lymphocyte-intrinsic defe...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065808/ https://ncbi.nlm.nih.gov/pubmed/24850719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400553 |
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