A Phase I Clinical Trial of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Patients with Recurrent Gynecologic Cancer

PURPOSE: Ad5.SSTR/TK.RGD is an infectivity-enhanced adenovirus expressing a therapeutic thymidine kinase suicide gene and a somatostatin receptor that allows for noninvasive gene transfer imaging. The purpose of this study was to identify the MTD, toxicities, clinical efficacy and biologic effects o...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kim, Kenneth H., Dmitriev, Igor, O’Malley, Janis P., Wang, Minghui, Saddekni, Souheil, You, Zhiying, Preuss, Meredith A., Harris, Raymond D., Aurigemma, Rosemarie, Siegal, Gene P., Zinn, Kurt R., Curiel, David T., Alvarez, Ronald D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065594/
https://ncbi.nlm.nih.gov/pubmed/22510347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2852
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items