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Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers
We report an aptamer discovery technology that reproducibly yields higher affinity aptamers in fewer rounds compared to conventional selection. Our method (termed particle display) transforms libraries of solution-phase aptamers into “aptamer particles”, each displaying many copies of a single seque...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065591/ https://ncbi.nlm.nih.gov/pubmed/24644057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201309334 |
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