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Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Targets
Many analytical techniques benefit greatly from the use of affinity reagent pairs, wherein each reagent recognizes a discrete binding site on a target. For example, antibody pairs have been widely used to dramatically increase the specificity of enzyme linked immunosorbent assays (ELISA). Nucleic ac...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382006/ https://ncbi.nlm.nih.gov/pubmed/22624874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300873p |
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