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Sex steroid levels and AD-like pathology in 3xTgAD mice

Decreases in testosterone (T) and 17β-oestradiol (E(2)) are associated with an increased risk for Alzheimer's disease (AD), which has been attributed to an increase in beta amyloid (Aβ) and tau pathologic lesions. While recent studies have used transgenic animal models to test the effects of se...

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Autori principali: Overk, Cassia R., Perez, Sylvia E., Ma, Chunqi, Taves, Matthew D., Soma, Kiran K., Mufson, Elliott J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065422/
https://ncbi.nlm.nih.gov/pubmed/22889357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2012.02374.x
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