Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

Predictive methods, physicochemical measurements, and structure activity relationship studies suggest that corticotropin-releasing factor (CRF; corticoliberin), its family members, and competitive antagonists (resulting from N-terminal deletions) usually assume an alpha-helical conformation when int...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gulyas, J, Rivier, C, Perrin, M, Koerber, S C, Sutton, S, Corrigan, A, Lahrichi, S L, Craig, A G, Vale, W, Rivier, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10575
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