Attenuated virulence of chitin-deficient mutants of Candida albicans.

We have analyzed the role of chitin, a cell-wall polysaccharide, in the virulence of Candida albicans. Mutants with a 5-fold reduction in chitin were obtained in two ways: (i) by selecting mutants resistant to Calcofluor, a fluorescent dye that binds to chitin and inhibits growth, and (ii) by disrup...

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-д хэвлэсэн:	Proc Natl Acad Sci U S A
Үндсэн зохиолчид:	Bulawa, C E, Miller, D W, Henry, L K, Becker, J M
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences 1995
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10570
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