Attenuated virulence of chitin-deficient mutants of Candida albicans.
We have analyzed the role of chitin, a cell-wall polysaccharide, in the virulence of Candida albicans. Mutants with a 5-fold reduction in chitin were obtained in two ways: (i) by selecting mutants resistant to Calcofluor, a fluorescent dye that binds to chitin and inhibits growth, and (ii) by disrup...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1995
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10570 |
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