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Attenuated virulence of chitin-deficient mutants of Candida albicans.

We have analyzed the role of chitin, a cell-wall polysaccharide, in the virulence of Candida albicans. Mutants with a 5-fold reduction in chitin were obtained in two ways: (i) by selecting mutants resistant to Calcofluor, a fluorescent dye that binds to chitin and inhibits growth, and (ii) by disrup...

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Библиографические подробности
Главные авторы: Bulawa, C E, Miller, D W, Henry, L K, Becker, J M
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC40653/
https://ncbi.nlm.nih.gov/pubmed/7479842
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