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Dual regulation of β(2)-adrenoceptor messenger RNA expression in human lung fibroblasts by β(2)–cAMP signaling; delayed upregulated inhibitors oppose a rapid in onset, direct stimulation of gene expression
Based on their bronchodilatory effect, β(2)-adrenoceptor agonists constitute essential elements in the treatment of bronchial asthma and COPD. As treatment with β(2)-adrenoceptor agonists has been associated with worsening of airway hyper-reactivity, possibly because of loss of β-adrenoceptor functi...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065340/ https://ncbi.nlm.nih.gov/pubmed/24705868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-014-0971-7 |
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