mTORC1 controls the adaptive transition of quiescent stem cells from G(0) to G(Alert)

A unique property of many adult stem cells is their ability to exist in a non-cycling, quiescent state(1). Although quiescence serves an essential role in preserving stem cell function until the stem cell is needed in tissue homeostasis or repair, defects in quiescence can lead to an impairment in t...

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Detalhes bibliográficos
Main Authors: Rodgers, Joseph T., King, Katherine Y., Brett, Jamie O., Cromie, Melinda J., Charville, Gregory W., Maguire, Katie K., Brunson, Christopher, Mastey, Namrata, Liu, Ling, Tsai, Chang-Ru, Goodell, Margaret A., Rando, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065227/
https://ncbi.nlm.nih.gov/pubmed/24870234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13255
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