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Assessment of PALB2 as a Candidate Melanoma Susceptibility Gene

Partner and localizer of BRCA2 (PALB2) interacts with BRCA2 to enable double strand break repair through homologous recombination. Similar to BRCA2, germline mutations in PALB2 have been shown to predispose to Fanconi anaemia as well as pancreatic and breast cancer. The PALB2/BRCA2 protein interacti...

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Bibliografski detalji
Glavni autori: Aoude, Lauren G., Xu, Mai, Zhao, Zhen Zhen, Kovacs, Michael, Palmer, Jane M., Johansson, Peter, Symmons, Judith, Trent, Jeffrey M., Martin, Nicholas G., Montgomery, Grant W., Brown, Kevin M., Hayward, Nicholas K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065098/
https://ncbi.nlm.nih.gov/pubmed/24949998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100683
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