High-Resolution Quantification of Hepatitis C Virus Genome-Wide Mutation Load and Its Correlation with the Outcome of Peginterferon-Alpha2a and Ribavirin Combination Therapy

Hepatitis C virus (HCV) is a highly mutable RNA virus and circulates as a heterogeneous population in individual patients. The magnitude of such population heterogeneity has long been proposed to be linked with diverse clinical phenotypes, including antiviral therapy. Yet data accumulated thus far a...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Weihua, Zhang, Xiaoan, Xu, Yanjuan, Weinstock, George M., Di Bisceglie, Adrian M., Fan, Xiaofeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065037/
https://ncbi.nlm.nih.gov/pubmed/24950220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100131
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