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Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy

Spinal and bulbar muscular atrophy is an X-linked degenerative motor neuron disease caused by an abnormal expansion in the polyglutamine encoding CAG repeat of the androgen receptor gene. There is evidence implicating endoplasmic reticulum stress in the development and progression of neurodegenerati...

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Detalhes bibliográficos
Main Authors: Montague, Karli, Malik, Bilal, Gray, Anna L., La Spada, Albert R., Hanna, Michael G., Szabadkai, Gyorgy, Greensmith, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065020/
https://ncbi.nlm.nih.gov/pubmed/24898351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu114
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