Loading...

Whole Genome and Exome Sequencing of Monozygotic Twins with Trisomy 21, Discordant for a Congenital Heart Defect and Epilepsy

Congenital heart defects (CHD) occur in 40% of patients with trisomy 21, while the other 60% have a structurally normal heart. This suggests that the increased dosage of genes on chromosome 21 is a risk factor for abnormal heart development. Interaction of genes on chromosome 21 or their gene produc...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chaiyasap, Pongsathorn, Kulawonganunchai, Supasak, Srichomthong, Chalurmpon, Tongsima, Sissades, Suphapeetiporn, Kanya, Shotelersuk, Vorasuk
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064986/
https://ncbi.nlm.nih.gov/pubmed/24950249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100191
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!