Translation of the radioresistance kinase TLK1B is induced by γ-irradiation through activation of mTOR and phosphorylation of 4E-BP1

BACKGROUND: The mammalian protein kinase TLK1 is a homologue of Tousled, a gene involved in flower development in Arabidopsis thaliana. The function of TLK1 is not well known, although knockout of the gene in Drosophila, or expression of a dominant negative mutant in mouse cells causes loss of nucle...

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Bibliographic Details
Main Authors: Sunavala-Dossabhoy, Gulshan, Fowler, Marcie, De Benedetti, Arrigo
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC406498/
https://ncbi.nlm.nih.gov/pubmed/15070431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-5-1
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