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HPLC–MS/MS method for the intracellular determination of ribavirin monophosphate and ribavirin triphosphate in CEM(ss) cells

A sensitive and specific method using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) for the determination of ribavirin monophosphate (RBV-MP) and ribavirin triphosphate (RBV-TP) in cells has been developed and validated. In this method, ribavirin phosphorylated metabol...

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Bibliografske podrobnosti
Main Authors: Meléndez, Margarita, Rosario, Osvaldo, Zayas, Beatriz, Rodríguez, José F.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064832/
https://ncbi.nlm.nih.gov/pubmed/19398292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2009.02.006
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