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The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells

BACKGROUND: Liver kinase 1 (LKB1) is an important multi-tasking protein linked with metabolic signaling, also controlling polarity and cytoskeletal rearrangements in diverse cell types including cancer cells. Prolactin (PRL) and Signal transducer and activator of transcription (STAT) proteins have b...

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Hlavní autoři: Linher-Melville, Katja, Singh, Gurmit
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064823/
https://ncbi.nlm.nih.gov/pubmed/24913037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-415
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