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Expression of xCT and activity of system x(c)(−) are regulated by NRF2 in human breast cancer cells in response to oxidative stress
Cancer cells adapt to high levels of oxidative stress in order to survive and proliferate by activating key transcription factors. One such master regulator, the redox sensitive transcription factor NF E2 Related Factor 2 (NRF2), controls the expression of cellular defense genes including those enco...
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| Опубликовано в: : | Redox Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392061/ https://ncbi.nlm.nih.gov/pubmed/25827424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.03.003 |
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