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Expression of xCT and activity of system x(c)(−) are regulated by NRF2 in human breast cancer cells in response to oxidative stress

Cancer cells adapt to high levels of oxidative stress in order to survive and proliferate by activating key transcription factors. One such master regulator, the redox sensitive transcription factor NF E2 Related Factor 2 (NRF2), controls the expression of cellular defense genes including those enco...

詳細記述

保存先:
書誌詳細
出版年:Redox Biol
主要な著者: Habib, Eric, Linher-Melville, Katja, Lin, Han-Xin, Singh, Gurmit
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392061/
https://ncbi.nlm.nih.gov/pubmed/25827424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.03.003
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