Membrane-Bound TRAIL Supplements Natural Killer Cell Cytotoxicity Against Neuroblastoma Cells

Neuroblastoma cells have been reported to be resistant to death induced by soluble, recombinant forms of TRAIL (CD253/TNFSF10) due to low or absent expression of caspase-8 and/or TRAIL-receptor 2 (TRAIL-R2/DR5/CD262/TNFRSF10b). However, their sensitivity to membrane-bound TRAIL on natural killer (NK...

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Main Authors: Sheard, Michael A., Asgharzadeh, Shahab, Liu, Yin, Lin, Tsen-Yin, Wu, Hong-Wei, Ji, Lingyun, Groshen, Susan, Lee, Dean A., Seeger, Robert C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064791/
https://ncbi.nlm.nih.gov/pubmed/23719242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31829b4493
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