Growth and Activation of Natural Killer Cells Ex Vivo from Children with Neuroblastoma for Adoptive Cell Therapy

PURPOSE: Adoptive transfer of natural killer (NK) cells combined with tumor-specific monoclonal antibodies (mAbs) has therapeutic potential for malignancies. We determined if large numbers of activated NK (aNK) cells can be grown ex vivo from peripheral blood mononuclear cells (PBMC) of children wit...

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Bibliographic Details
Main Authors: Liu, Yin, Wu, Hong-Wei, Sheard, Michael A., Sposto, Richard, Somanchi, Srinivas S., Cooper, Laurence J.N., Lee, Dean A., Seeger, Robert C.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658308/
https://ncbi.nlm.nih.gov/pubmed/23378384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1243
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