Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGFβ1

BACKGROUND: Treatment for children with high-risk neuroblastoma with anti-disialoganglioside mAb ch14.18, IL-2, and GM-CSF plus 13-cis-retinoic acid after myeloablative chemotherapy improves survival, but 40 % of patients still relapse during or after this therapy. The microenvironment of high-risk...

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Библиографические подробности
Главные авторы: Xu, Yibing, Sun, Jianping, Sheard, Michael A., Tran, Hung C., Wan, Zesheng, Liu, Wei Yao, Asgharzadeh, Shahab, Sposto, Richard, Wu, Hong Wei, Seeger, Robert C.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2013
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907789/
https://ncbi.nlm.nih.gov/pubmed/23982484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1466-y
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