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Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

Androgens and the androgen receptor (AR) play important roles in male fertility, although the detailed mechanisms, particularly how androgen/AR influences spermatogenesis in particular cell types, remain unclear. Using a Cre-Lox conditional knockout strategy, we generated a tissue-specific knockout...

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Hlavní autoři: Chang, Chawnshang, Chen, Yen-Ta, Yeh, Shauh-Der, Xu, Qingquan, Wang, Ruey-Sheng, Guillou, Florian, Lardy, Henry, Yeh, Shuyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC406435/
https://ncbi.nlm.nih.gov/pubmed/15107499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307306101
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