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Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

Androgens and the androgen receptor (AR) play important roles in male fertility, although the detailed mechanisms, particularly how androgen/AR influences spermatogenesis in particular cell types, remain unclear. Using a Cre-Lox conditional knockout strategy, we generated a tissue-specific knockout...

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Bibliografiske detaljer
Main Authors: Chang, Chawnshang, Chen, Yen-Ta, Yeh, Shauh-Der, Xu, Qingquan, Wang, Ruey-Sheng, Guillou, Florian, Lardy, Henry, Yeh, Shuyuan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC406435/
https://ncbi.nlm.nih.gov/pubmed/15107499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307306101
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