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Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells

Using a Cre-Lox conditional knockout strategy, we generated a germ cell-specific androgen receptor (AR) knockout mouse (G-AR(−/y)) with normal spermatogenesis. Sperm count and motility in epididymis from AR(−/y) mice are similar to that of WT (G-AR(+/y)) mice. Furthermore, fertility tests show there...

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Detalhes bibliográficos
Main Authors: Tsai, Meng-Yin, Yeh, Shauh-Der, Wang, Ruey-Sheng, Yeh, Shuyuan, Zhang, Caixia, Lin, Hung-Yun, Tzeng, Chii-Ruey, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748162/
https://ncbi.nlm.nih.gov/pubmed/17142319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608565103
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