HLA typing from RNA-Seq sequence reads

We present a method, seq2HLA, for obtaining an individual's human leukocyte antigen (HLA) class I and II type and expression using standard next generation sequencing RNA-Seq data. RNA-Seq reads are mapped against a reference database of HLA alleles, and HLA type, confidence score and locus-spe...

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Bibliografische gegevens
Hoofdauteurs: Boegel, Sebastian, Löwer, Martin, Schäfer, Michael, Bukur, Thomas, de Graaf, Jos, Boisguérin, Valesca, Türeci, Özlem, Diken, Mustafa, Castle, John C, Sahin, Ugur
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064318/
https://ncbi.nlm.nih.gov/pubmed/23259685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm403
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