Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

BACKGROUND: Human papillomavirus positive (HPV+) head and neck squamous cell carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and epidemiological entity. Understanding the genetic basis of this specific subtype of cancer could allow therapeutic targeting of affected pathway...

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Main Authors: Lechner, Matthias, Frampton, Garrett M, Fenton, Tim, Feber, Andrew, Palmer, Gary, Jay, Amrita, Pillay, Nischalan, Forster, Martin, Cronin, Maureen T, Lipson, Doron, Miller, Vincent A, Brennan, Timothy A, Henderson, Stephen, Vaz, Francis, O'Flynn, Paul, Kalavrezos, Nicholas, Yelensky, Roman, Beck, Stephan, Stephens, Philip J, Boshoff, Chris
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064312/
https://ncbi.nlm.nih.gov/pubmed/23718828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm453
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