Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

BACKGROUND: Human papillomavirus positive (HPV+) head and neck squamous cell carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and epidemiological entity. Understanding the genetic basis of this specific subtype of cancer could allow therapeutic targeting of affected pathway...

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Detalhes bibliográficos
Main Authors: Lechner, Matthias, Frampton, Garrett M, Fenton, Tim, Feber, Andrew, Palmer, Gary, Jay, Amrita, Pillay, Nischalan, Forster, Martin, Cronin, Maureen T, Lipson, Doron, Miller, Vincent A, Brennan, Timothy A, Henderson, Stephen, Vaz, Francis, O'Flynn, Paul, Kalavrezos, Nicholas, Yelensky, Roman, Beck, Stephan, Stephens, Philip J, Boshoff, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064312/
https://ncbi.nlm.nih.gov/pubmed/23718828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm453
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