Intranasal Delivery of Cell-Penetrating anti-NF-κB Peptides (Tat-NBD) Alleviates Infection-Sensitized Hypoxic-Ischemic Brain Injury

Perinatal infection aggravates neonatal hypoxic-ischemic (HI) brain injury and may interfere with therapeutic hypothermia. While the NF-κB signaling pathway has been implicated in microglia activation in infection-sensitized HI, the current therapeutic strategies rely on systemic intervention, which...

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Main Authors: Yang, Dianer, Sun, Yu-Yo, Lin, Xiaoyi, Baumann, Jessica M., Dunn, R. Scott, Lindquist, Diana M., Kuan, Chia-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064308/
https://ncbi.nlm.nih.gov/pubmed/23353638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.01.015
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