Blocking Lymphocyte Trafficking with FTY720 Prevents Inflammation-Sensitized Hypoxic–Ischemic Brain Injury in Newborns

Intrauterine infection (chorioamnionitis) aggravates neonatal hypoxic–ischemic (HI) brain injury, but the mechanisms linking systemic inflammation to the CNS damage remain uncertain. Here we report evidence for brain influx of T-helper 17 (T(H)17)-like lymphocytes to coordinate neuroinflammatory res...

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Опубликовано в: :J Neurosci
Главные авторы: Yang, Dianer, Sun, Yu-Yo, Bhaumik, Siddhartha Kumar, Li, Yikun, Baumann, Jessica M., Lin, Xiaoyi, Zhang, Yujin, Lin, Shang-Hsuan, Dunn, R. Scott, Liu, Chia-Yang, Shie, Feng-Shiun, Lee, Yi-Hsuan, Wills-Karp, Marsha, Chougnet, Claire A., Kallapur, Suhas G., Lewkowich, Ian P., Lindquist, Diana M., Murali-Krishna, Kaja, Kuan, Chia-Yi
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2014
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252554/
https://ncbi.nlm.nih.gov/pubmed/25471584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2582-14.2014
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