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Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts generated by four different...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406421/ https://ncbi.nlm.nih.gov/pubmed/15043764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-1336-2-1 |
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