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Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor

BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts generated by four different...

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Bibliografske podrobnosti
izdano v:Nucl Recept
Main Authors: Arnold, Katja A, Eichelbaum, Michel, Burk, Oliver
Format: Artigo
Jezik:Inglês
Izdano: BMC 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC406421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15043764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1478-1336-2-1
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