Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor

BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts generated by four different...

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Hlavní autoři: Arnold, Katja A, Eichelbaum, Michel, Burk, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC406421/
https://ncbi.nlm.nih.gov/pubmed/15043764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-1336-2-1
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