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Pierced Lasso Bundles Are a New Class of Knot-like Motifs
A four-helix bundle is a well-characterized motif often used as a target for designed pharmaceutical therapeutics and nutritional supplements. Recently, we discovered a new structural complexity within this motif created by a disulphide bridge in the long-chain helical bundle cytokine leptin. When o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063663/ https://ncbi.nlm.nih.gov/pubmed/24945798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003613 |
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