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Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse

The vascular endothelium expresses endothelial nitric oxide synthase (eNOS) that generates nitric oxide (NO) to help maintain vascular integrity due to its anti-inflammatory, antiproliferative, and antithrombogenic effects. Pharmacological blockade of NO production has been shown to exacerbate renal...

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Main Authors: Nakayama, Takahiro, Sato, Waichi, Kosugi, Tomoki, Zhang, Li, Campbell-Thompson, Martha, Yoshimura, Ashio, Croker, Byron P., Johnson, Richard J., Nakagawa, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063508/
https://ncbi.nlm.nih.gov/pubmed/19036847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90450.2008
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