Modification of Microbial Polymalic Acid With Hydrophobic Amino Acids for Drug-Releasing Nanoparticles

[Image: see text] Microbial poly(β, l-malic acid) was modified with either l-leucine ethyl ester (L) or l-phenylalanine methyl ester (F) to produce amphiphylic copolymers. The degradation of these copolymers in aqueous buffer took place under physiological conditions in a few weeks by hydrolysis of...

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Hauptverfasser: Lanz-Landázuri, Alberto, García-Alvarez, Montserrat, Portilla-Arias, José, de Ilarduya, Antxon Martínez, Holler, Eggehard, Ljubimova, Julia, Muñoz-Guerra, Sebastián
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063452/
https://ncbi.nlm.nih.gov/pubmed/24954994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/macp.201200134
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