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The optimization of polymalic acid peptide copolymers for endosomolytic drug delivery

Membranolytic macromolecules are promising vehicles forcytoplasmic drug delivery, but their efficiency and safety remains primary concerns. To address those concerns, membranolytic properties of various poly(β-l-malic acid) (PMLA) copolymers were extensively investigated as a function of concentrati...

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Detalhes bibliográficos
Main Authors: Ding, Hui, Portilla-Arias, Jose, Patil, Rameshwar, Black, Keith L., Ljubimova, Julia Y., Holler, Eggehard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110056/
https://ncbi.nlm.nih.gov/pubmed/21514661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.03.073
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