Poly(methyl malate) Nanoparticles: Formation, Degradation, and Encapsulation of Anticancer Drugs

PMLA nanoparticles with diameters of 150–250 nm are prepared, and their hydrolytic degradation is studied under physiological conditions. Degradation occurs by hydrolysis of the side chain methyl ester followed by cleavage of the main-chain ester group with methanol and L-malic acid as the final deg...

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Detalhes bibliográficos
Main Authors: Lanz-Landázuri, Alberto, García-Alvarez, Montserrat, Portilla-Arias, José, de Ilarduya, Antxon Martínez, Patil, Rameshwar, Holler, Eggehard, Ljubimova, Julia Y., Muñoz-Guerra, Sebastián
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496083/
https://ncbi.nlm.nih.gov/pubmed/21793213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201100107
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