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Drugs for Allosteric Sites on Receptors
The presence of druggable, topographically distinct allosteric sites on a wide range of receptor families has offered new paradigms for small molecules to modulate receptor function. Moreover, ligands that target allosteric sites offer significant advantages over the corresponding orthosteric ligand...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063350/ https://ncbi.nlm.nih.gov/pubmed/24111540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010611-134525 |
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