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Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ
B-RafV600E inhibitors have been suggested to promote tumor regression with the help of host immunity, but this hypothesis has not been examined directly in detail. In this study, we profiled immunological changes in the tumor microenvironment and tumor infiltrating lymphocytes (TILs) in a B-RafV600E...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063281/ https://ncbi.nlm.nih.gov/pubmed/24736544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3461 |
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