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Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells

The mechanism of cisplatin resistance in cancer cells is not fully understood. Here, we show that the Akt/mTOR survival pathway plays an important role in cisplatin resistance in human ovarian cancer cells. Specifically, we found that cisplatin treatment activates the Akt/mTOR survival pathway and t...

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Bibliografiske detaljer
Main Authors: Peng, Dong-Jun, Wang, Juan, Zhou, Jun-Ying, Wu, Gen Sheng
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063277/
https://ncbi.nlm.nih.gov/pubmed/20214883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.03.029
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