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Synthesis of Angularly Substituted Trans-Fused Hydroindanes by Convergent Coupling of Acyclic Precursors

[Image: see text] Angularly substituted trans-fused hydroindanes are now accessible by the direct and convergent union of trimethylsilyl (TMS)-alkynes with 4-hydroxy-1,6-enynes by a process that forges three C–C bonds, one C–H bond, and two new stereocenters. The annulation is proposed to proceed by...

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Bibliografiske detaljer
Main Authors: Jeso, Valer, Aquino, Claudio, Cheng, Xiayun, Mizoguchi, Haruki, Nakashige, Mika, Micalizio, Glenn C.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063191/
https://ncbi.nlm.nih.gov/pubmed/24856045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja504374j
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