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Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance
[Image: see text] EmrE is a multidrug resistance efflux pump with specificity to a wide range of antibiotics and antiseptics. To obtain atomic-scale insight into the attributes of the native state that encodes the broad specificity, we used a hybrid of solution and solid-state NMR methods in lipid b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063181/ https://ncbi.nlm.nih.gov/pubmed/24856154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503145x |
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