Ligand-Induced Conformational Changes of the Multidrug Resistance Transporter EmrE Probed by Oriented Solid-State NMR Spectroscopy

[Image: see text] We used oriented solid-state NMR spectroscopy and biochemical cross-linking experiments to demonstrate that the ligand-free membrane protein transporter EmrE forms anti-parallel dimers with different monomer tilt angles relative to the lipid bilayer. Our results also show the subtl...

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Hlavní autoři: Gayen, Anindita, Banigan, James R., Traaseth, Nathaniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876743/
https://ncbi.nlm.nih.gov/pubmed/23939862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201303091
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