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Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide

In a mouse model of breast carcinoma, the combination of cyclophosphamide and transforming growth factor β1,2,3 (TGFβ1,2,3)-targeting antibody achieved superior antineoplastic effects. This novel paradigm of synergistic chemoimmunotherapy promises to improve the clinical outcome of cancer patients w...

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Detalhes bibliográficos
Main Authors: Chen, Xin, Wakefield, Lalage M, Oppenheim, Joost J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063140/
https://ncbi.nlm.nih.gov/pubmed/25050195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28247
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