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Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide
In a mouse model of breast carcinoma, the combination of cyclophosphamide and transforming growth factor β1,2,3 (TGFβ1,2,3)-targeting antibody achieved superior antineoplastic effects. This novel paradigm of synergistic chemoimmunotherapy promises to improve the clinical outcome of cancer patients w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063140/ https://ncbi.nlm.nih.gov/pubmed/25050195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28247 |
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